The key to longevity lies in the mind, says The Kusnacht Practice’s Dr Antoinette Sarasin
Poor mental health is both a cause and symptom of unhealthy, self-destructive behaviours that can become embedded as habits, driving a lifestyle that will almost certainly reduce longevity
29 December, 2025
TT
16
The topic of longevity is more than a fad; the desire for a long life has been around since the dawn of human history, but lately, it has become a modern-world obsession. Fuelled by high-profile figures such as tech entrepreneur Bryan Johnson, whose Netflix documentary records his quest to challenge mortality, as well as by other media and social pressures, the wish to live forever has gone mainstream.
For most would-be Bryan Johnsons, investing millions of dollars into such an extreme and intricate regimen just isn’t an option – but there is no doubt that tech advances are paving the way for us all to gain the one thing that is never promised: time. From NAD boosters to oxygen and red-light therapy, genetic and microbiome testing, regenerative therapies and biohacking to levels we never thought possible… aids to longevity come in myriad shapes, sizes and molecular makeup.
Scientifically, these things work. But we also need to look at longevity through a different lens: while the industry is full of research-driven, pioneering medicines, treatments and screenings, when you strip longevity back to its essence, the impact of mental health is key.
While extending life has become both a scientific frontier and a cultural phenomenon, the important question that we need to ask is this: to what extent can technology help us live forever, if the mind isn’t ‘in’?
Mental health is a central pillar of healthy ageing – which isn’t just about how long you live, but how well you live. More and more, research shows that our emotional and psychological wellbeing is deeply intertwined with our physical health and, consequently, our ability to age well.
An estimated 80 per cent of chronic diseases, such as type 2 diabetes, cardiovascular disease and certain cancers, are preventable through lifestyle. That umbrella term includes diet and exercise, yes, but also stress management, sleep quality, social connections and purpose – all core components of mental health.
Lifestyle is the sum of people’s habits
Each person’s lifestyle is the sum of their habits, which drive their choices and behaviour (often subconsciously) and are driven by their mental state. Good mental health creates constructive habits and thus, a healthier lifestyle.
Poor mental health is both a cause and symptom of unhealthy, self-destructive behaviours that can become embedded as habits, driving a lifestyle that will almost certainly reduce longevity.
While the human brain has a remarkable capacity to create new (and positive) habits, poor mental health can make it significantly more difficult to change bad habits and to maintain good ones. Put simply, mental health is a prerequisite for a healthy lifestyle.
Despite all of the pioneering science behind longevity, it is apparent that lifestyle habits are key to a longer, healthier life – and can add up to 20 years to your life. Good mental health and the ability to master behavioural shifts are imperative to prolonging healthspan.
Underlining the impact that mental health has on ageing, a landmark study by Harvard, one of the longest-running in history, found that robust social connections were the strongest predictor of a longer, healthier life.
Participants who reported feeling happier and more connected were not only healthier but lived significantly longer than those who felt isolated.
We also know that chronic stress or anxiety accelerates cellular ageing, disrupts immune function and contributes to inflammation, all of which are known drivers of age-related diseases.
Practices that foster mental wellbeing by reducing stress, such as mindfulness, psychotherapy, somatic movement and yoga, can slow biological ageing and promote neuroplasticity, the brain’s ability to adapt and grow throughout life.
Relationship between a healthy mind and a sound body
With this growing understanding of the profound relationship between a healthy mind and a physically sound body, the longevity narrative today is shifting toward mental wellness as a proactive strategy in the science of ageing.
Longevity isn’t just about adding years to your life; it’s about adding life to your years, and it means investing in yourself. This may not come in the form of cutting-edge biotech, but in the real fundamentals – particularly one’s mental health: building emotional resilience, meaningful relationships and psychological wellbeing.
The most advanced tool we have for ageing well may not be a futuristic pill or a cryo-chamber but the human mind itself.
Dr Antoinette Sarasin is the director of Precision Medicine, a member of the Board of Directors, and founder of the Biomolecular Restoration Method at The Kusnacht Practice.



















