Oracle Cloud Infrastructure to deploy 50,000 AMD GPUs for large-scale AI

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Oracle and AMD have announced a major expansion of their long-standing collaboration to help enterprises scale their artificial intelligence capabilities. Building on years of co-innovation, Oracle Cloud Infrastructure (OCI) will serve as a launch partner for the first publicly available AI supercluster powered by AMD Instinct MI450 Series GPUs. The deployment will begin with 50,000 GPUs in Q3 2026, with further expansion planned for 2027 and beyond.

The latest announcement builds on Oracle and AMD’s joint efforts to provide AMD Instinct GPU platforms on OCI. Following the launch of AMD Instinct MI300X powered shapes in 2024, OCI will extend availability to AMD Instinct MI355X GPUs as part of the zettascale OCI Supercluster.

As AI models grow increasingly complex and data-intensive, enterprises are seeking flexible, high-performance infrastructure solutions engineered for scale and efficiency. OCI’s upcoming AI superclusters will feature AMD’s “Helios” rack design, powered by AMD Instinct MI450 Series GPUs, next-generation AMD EPYC CPUs (codenamed “Venice”), and AMD Pensando advanced networking (codenamed “Vulcano”). This vertically integrated, rack-scale system is designed to deliver optimal performance, scalability, and energy efficiency for large-scale AI workloads.

“Our customers are building some of the world’s most ambitious AI applications, and that requires robust, scalable, and high-performance infrastructure,” said Mahesh Thiagarajan, executive vice president, Oracle Cloud Infrastructure. “By bringing together the latest AMD processor innovations with OCI’s secure, flexible platform and advanced networking powered by Oracle Acceleron, customers can push the boundaries with confidence. Through our decade-long collaboration with AMD—from EPYC to AMD Instinct accelerators—we’re continuing to deliver the best price-performance, open, secure, and scalable cloud foundation in partnership with AMD to meet customer needs for this next era of AI.”

“AMD and Oracle continue to set the pace for AI innovation in the cloud,” said Forrest Norrod, executive vice president and general manager, Data Center Solutions Business Group, AMD. “With our AMD Instinct GPUs, EPYC CPUs, and advanced AMD Pensando networking, Oracle customers gain powerful new capabilities for training, fine-tuning, and deploying the next generation of AI. Together, AMD and Oracle are accelerating AI with open, optimised, and secure systems built for massive AI data centers.”

The expanded partnership reflects both companies’ strategic alignment in advancing AI infrastructure at scale — combining Oracle’s cloud architecture with AMD’s compute and networking innovations to power the next wave of enterprise AI.