Talks between the United States and Iran have broken down in Islamabad after 21 hours of negotiations, with US Vice President JD Vance confirming that no agreement was reached.
Speaking on Sunday, Vance said the US delegation would leave Pakistan without a deal, citing Iran’s refusal to accept Washington’s terms — particularly around its nuclear programme.
“The bad news is that we have not reached an agreement, and I think that’s bad news for Iran much more than it’s bad news for the United States of America,” Vance said. “So we go back to the United States having not come to an agreement. We’ve made very clear what our red lines are.”
He added that a central sticking point was securing firm assurances from Iran that it would not pursue nuclear weapons capabilities.
“The simple fact is that we need to see an affirmative commitment that they will not seek a nuclear weapon and they will not seek the tools that will enable them to quickly achieve a nuclear weapon,” Vance said, describing the issue as a “core goal” of US President Donald Trump.
Vance also indicated that the US had shown flexibility during the negotiations but ultimately could not bridge the gap.
“We just could not get to a situation where the Iranians were willing to accept our terms,” he said, adding: “I think we were quite flexible, we were quite accommodating.”
The vice president said he had been in close contact with Trump throughout the talks, speaking to him “half a dozen times” during the negotiating process.
The high-stakes discussions — the first direct US-Iran talks in more than a decade — were seen as critical to determining the future of a fragile two-week ceasefire, as well as the potential reopening of the Strait of Hormuz, a key global shipping route through which around a fifth of the world’s energy supplies pass.
Iran has restricted access to the strait since the conflict began in late February, contributing to volatility in global oil markets and disruption to trade flows.
In a post on X, Iran’s government confirmed that the talks had concluded, but signalled that diplomatic efforts would continue.
“Negotiations will continue despite some remaining differences,” the statement said, adding that technical experts from both sides would exchange documents. No timeline was provided for the next round of discussions.
The breakdown leaves uncertainty over the next phase of diplomacy, with markets and policymakers closely watching whether talks can resume — and whether progress can be made on the nuclear issue that remains at the centre of the dispute.