Back pain rarely makes the morning briefing, yet it may be the most consequential health condition no one is treating as a strategic problem. The World Health Organization (WHO) estimates that 619 million people globally were living with low back pain in 2020 — a 60 per cent jump since 1990 — and projections in The Lancet Rheumatology forecast 843 million cases by 2050.
WHO classifies low back pain as the leading cause of disability worldwide, with around 70 per cent of years lost to back-pain disability falling in the 20-to-65 working-age band.
Most back pain does not require an operating theatre. The challenge is sorting the cases that genuinely benefit from surgery from the much larger group that does not.
Few institutions have spent more time on that question than Mayo Clinic, consistently ranked at the top of US hospital rankings for orthopaedics and neurosurgery. Dr Ahmad Nassr is an orthopaedic spine surgeon there. He spoke to us about what’s driving the burden, how the technology is shifting, and what patients should watch next.
Low back pain is the leading cause of disability worldwide. What’s behind this growing burden, and what does the picture look like in the UAE and wider Middle East?
Low back pain is the leading cause of years lived with disability globally, affecting hundreds of millions of people at any given time. The reasons are multifactorial, but several trends are consistent worldwide, including in the Middle East.
Populations are ageing, and spinal degeneration is cumulative. At the same time, rising rates of obesity and metabolic disease are accelerating disc degeneration and increasing mechanical stress on the spine.
We are also seeing more sedentary lifestyles, with prolonged sitting and reduced physical activity contributing to deconditioning of the musculature that supports the spine.
In regions like the UAE, these factors are often amplified by rapid urbanisation and lifestyle changes. The result is that patients are developing symptomatic spinal conditions earlier and living longer with them.
Importantly, most back pain still does not require surgery. Mayo Clinic takes a personalised approach to care, including identifying patients who will benefit from surgery.
Spine surgery still carries a perception of being highly invasive. How much has that reality changed?
The perception is outdated, but it hasn’t completely disappeared. Over the past decade, spine surgery has evolved significantly. Many procedures that once required large exposures can now be performed through more targeted, tissue-sparing approaches, resulting in shorter hospital stays and faster recovery.
That said, it’s important not to oversimplify this. Spine surgery is a surgical operation, and it should not be taken lightly. The more meaningful advancement is not just that procedures are less invasive, but that we are far more precise in determining who actually needs surgery — and who does not.
At Mayo Clinic, how are innovations like motion-preserving implants, robotics, and AI being integrated into everyday patient care?
At Mayo Clinic, new technologies are integrated when they provide clear value to patients. Motion-preserving implants are one example. Traditionally, many spinal conditions were treated with fusion, which eliminates motion at a segment of the spine.
Newer technologies aim to preserve motion while still addressing the underlying pathology.
These are not appropriate for every patient, but in selected cases, they may help maintain more normal spinal mechanics.
Robotics and advanced navigation have improved the accuracy and consistency of procedures such as spinal instrumentation, particularly in complex cases.
Artificial intelligence is an emerging tool in areas such as imaging interpretation, surgical planning, and outcome prediction. While still evolving, it has the potential to further refine how we match treatments to individual patients.
Ultimately, these are tools. The benefit comes from thoughtful application, not from the technology itself.
What sets Mayo Clinic’s approach to spine treatment apart from other institutions globally?
We are the largest integrated, not-for-profit medical group practice in the world. We specialise in complex cases.The defining feature is a patient-centered, multidisciplinary approach combined with a strong emphasis on appropriate care.
Patients are not directed toward surgery by default. In fact, the majority of patients we evaluate do not undergo an operation. A significant effort is made to identify the true source of symptoms and to pursue nonoperative care when appropriate.
When surgery is indicated, it is done with a clear objective and a focus on durable, long-term outcomes rather than short-term fixes. Care decisions are also made collaboratively across specialties, including orthopedic surgery, neurosurgery, pain medicine, and rehabilitation. This allows for a more comprehensive and balanced approach to treatment.
There is also a strong culture of evaluating outcomes and continuously refining care pathways based on data and experience.
What’s the next big shift in spine care that patients should be watching closely?
The next major shift is toward even more personalised and function-preserving care. There is also increasing focus on motion preservation and restoring more normal spinal function.
Looking further ahead, biologic therapies aimed at slowing or reversing disc degeneration are an area of active research and hold promise, although they are not yet ready for routine clinical use.
The overarching trend is precision. At Mayo Clinic, we focus on delivering the right treatment to the right patient at the right time.